Skip to main content
. 2009 Sep;175(3):1246–1254. doi: 10.2353/ajpath.2009.090042

Figure 3.

Figure 3

The MMTV-EZH2 transgene induces precocious hyperplasia in nulliparous female transgenic mice. A: Whole mount of mammary glands from 4-month-old nulliparous female wild-type (wt) and MMTV-EZH2 mice showing ductal hyperplasia in the MMTV-EZH2 glands. Note the increased numbers of secondary and tertiary ductal branches and larger TEBs in MMTV-EZH2 mice. B: MMTV-EZH2 mice have increased secondary and tertiary branches compared with wild-type virgin mice at 4 months of age (n = 5 in each group, Student’s t-test, *P < 0.001 for both, error bars = SD).