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. 2009 Sep 3;4(9):e6845. doi: 10.1371/journal.pone.0006845

Figure 2. Effect of HoxA-11 knockdown on intrinsic HoxA-11 and PRL mRNA expression.

Figure 2

The expression of PRL (dark gray bars) and HoxA-11 (light gray bars) was assayed in undifferentiated, mock-transfected ESC (UnDiff), or in differentiated cells (Diff) that had not been transfected (No Treat.) or had been transfected with random sequence siRNA control (siRNA-Co), or with two different siRNAs targeting HoxA-11 (siRNA-1, siRNA-2). Results are shown as fold changes relative to expression levels in differentiated control cells (set to 1). n = 6 replicate experiments, means±SEM. *, P<0.05; ***, P<0.001 (t-test compared to No Treat.).