Figure 3. Time courses of irreversible inhibition for mosquito and human AChEs by AMTS13.

Extracts of An. gambiae s. str. larva and rhAChE were exposed, respectively, to 6 µM AMTS13 at room temperature for defined intervals of time terminated by addition of glutathione (to a final concentration of 500 µM). Shown is AChE activity in treated samples assayed radiometrically.