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. 2009 Sep 4;5(9):e1000568. doi: 10.1371/journal.ppat.1000568

Figure 4. L. monocytogenes within a phagosome suppress the host inflammatory response to bacteria within the cytosol.

Figure 4

(A) Mice were infected with 1×105 CFU ActA-Lm–OVA alone, or in combination with increasing doses of LLO-Lm-OVA. Serum was collected 24 hours later and assayed for IFN-γ, IL-12p70, IL-6, and MCP-1. (B) C57Bl/6 and B6.MyD88−/− mice were infected with 1×105 CFU ActA-Lm–OVA, 1×108 CFU LLO-Lm-OVA, or the combination of both strains. Serum was collected 4 hours later and assayed for IL-10 and IL-12p40. Bars represent the mean and standard error of 5 mice per group.