Table 1.
Treatment | Author | n | Recurrence (%) | 5-yr survival (%) |
Liver resection | ||||
Ercolani (2003)[61] | 224 | 54.4 | 42.0 | |
Sim (2003)[62] | 81 | NS | 59.01 | |
Belghiti (2003)[63] | 328 | NS | 37.0 | |
Bartlett (2007)[59] | 53 | 47.0 | 42.6 | |
Nuzzo (2007)[64] | 248 | 46.0 | 24.0 | |
Deceased donor liver transplantation | ||||
Mazzaferro (1996) (Milan criteria)[33] | 48 | 8.0 | 75.42 | |
Jonas (2001) (Milan criteria)[65] | 120 | 16.0 | 71.0 | |
Figueras (2001) (5 cm, localised)[66] | 307 | 21.0 | 63.0 | |
Yao (2001) (UCSF criteria)[34] | 70 | 11.4 | 75.2 | |
Decaens (2006)[36] | ||||
Milan criteria | 279 | NS | 60.0 | |
Beyond Milan, but within UCSF | 44 | NS | 45.6 | |
Beyond UCSF and Milan criteria | 145 | NS | 34.7 | |
Living donor liver transplantation | ||||
Todo (2007)[67] | ||||
Milan criteria | 137 | 1.4 | 79.41 | |
Extended criteria | 172 | 22.2 | 60.0 | |
Hwang (2005)[68] | ||||
Milan criteria | 173 | NS | 88.0 | |
Extended criteria | 64 | NS | 60.01 | |
Jonas (2007)[69] | ||||
Milan criteria | 8 | NS | 75.0 | |
Extended criteria | 13 | NS | 62.0 | |
Kwon (2007)[70] | ||||
Extended criteria | 139 | NS | 79.9 | |
Sugawara (2007)[71] | ||||
Extended criteria (5 nodules <5cm) | 78 | 10.0 | 75.0 | |
Soejima (2007)[40] | ||||
Milan criteria | 16 | 0.0 | 100 | |
Unlimited criteria | 44 | 18.2 | 74.01 | |
Salvage liver transplantation | ||||
Belghiti (2003)[55] | 18 | 5.6 | 61.0 | |
Schwartz (2006)[19] | 18 | 44.0 | NS | |
Hwang (2007)[54] | 17 | NS | NS |
NS: Not stated; UCSF: University of California San Francisco.
3-year survival;
4-year survival.