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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Expert Opin Investig Drugs. 2009 May;18(5):573–584. doi: 10.1517/13543780902810345

Table 1.

Classes and specificities of HDAC inhibitors.

HDAC inhibitor Target
Hydroxamates
TSA Class I and
II HDACs
SAHA/Zolinza/vorinostat Class I and
II HDACs
LAQ-824 Class I and
II HDACs
LBH-589/panobinostat Class I and
II HDACs
PCI 24789 Class I and
II HDACs
Aliphatic acids
VPA Class I and
lla HDACs
Sodium Phenylbutyrate Class I and
lla HDACs
Sodium Butyrate Class I and
lla HDACs
Cyclic tetrapeptides
Apicidin Class I and III
HDACs
Trapoxin Class I and IIa
HDACs
Depsipeptide/FK-228/
romidepsin
Class IHDACs
Benzamides
M5-275/SNDX-275 HDAC-l,
HDAC-2,
HDAC-3
MGCD0103 Class I HDACs

SAHA: Suberoylanilide hydroxamic acid; SB: Sodium butyrate; TSA: Trichostatin A; VPA: Valproic acid.