Table 2.
Demographic, clinical, and imaging data of the RRMS patients
| RRMS Patients | Men | Women | Men & Women | Men vs. Women (p) |
|---|---|---|---|---|
| Number of Patients | 8 | 24 | 32 | 0.005 (χ2-test) |
| *Age (years) | 40.9 ± 8.5 | 42.2± 8.6 | 41.9 ± 8.5 | 0.72 (t-test) |
| 25.6–50.1 | 21.9–56.6 | 21.9–56.6 | ||
| 41.8 | 43.7 | 43.3 | ||
| DD (years) | 5.8 ± 7.2 | 9.8 ± 8.0 | 9.0 ± 9.0 | 0.22 (t-test) |
| 0.2–22.3 | 0.4–30.3 | 0.2–30.3 | ||
| 2.5 | 8.8 | 6.3 | ||
| EDSS | 1.5 ± 1.0 | 1.7 ± 1.6 | 1.7 ± 1.5 | 0.46 |
| 0.0–3 | 0–6.5 | 0.0–6.5 | (Mann-Whitney) | |
| 1.75 | 1.75 | 1.75 | ||
| Lesion Volume (mL) | 11.7 ± 15.9 | 14.6± 13.1 | 10.9 ± 116 | |
| 0–47.2 | 1.3–41.6 | 0–47.2 | 0.61 (t-test) | |
| 5.1 | 12.3 | 9.8 | ||
| ICV (mL) | 1562.0 ± 140.9 | 1453.8 ± 120.6 | 1480.9 ± 132.5 | 0.04 (t-test) |
| CNV (mL) | 6.54 ± 1.14 | 5.95 ± 0.94 | 6.1 ± 1.00 | 0.15 (t-test) |
| CNVp = CNV/ICV*100 % | 0.422 ± 0.085 | 0.412 ± 0.076 | 0.415 ± 0.077 | 0.75 (t-test) |
| WBCSFp = CSFv/ICV*100 % | 12.5 ± 3.6 | 13.9 ± 4.1 | 13.6 ± 4.0 | 0.38 (t-test) |
| WBLVp = LV/ICV*100 % (Mean ± SD), [Min-Max], Median |
0.78 ± 1.03 | 1.0 ± 0.90 | 0.93 ± 0.95 | 0.57 (t-test) |
| [0–3], 0.30 | [0.1–2.9], 0.80 | [0–3], 0.65 | ||
*
Mean and standard deviation values (mean ± SD) are reported, range [min-to-max] and median
DD = Disease Duration; EDSS = Expanded Disability Status Score; RRMS= Relapsing and Remitting Multiple Sclerosis; WBLVp = Whole Brain Lesion Volume Percentage (LV/ICV *100%).