Table 3.
Comparison between controls and RRMS age and group means of various MRI-xderived parameters of the entire caudate (fractional anisotropy, mean diffusivity and T2 relaxation time) along with the age linear regression and correlation statistical analysis.
| Healthy Adult Controls | RRMS | p | |
|---|---|---|---|
| Age (years) | 38.2 ± 11.4 | 41.9 ± 8.5 | 0.15 |
| ICV (mL = cm3) | 1527.3 ± 137.8 | 1480.9 ± 132.5 | 0.17 |
| WBCSFp | 10.1 ± 2.8 | 13.6 ± 4.0 | 0.0001 |
| CNV (mL) | 7.18 ± 0.84 | 6.1 ± 1.01 | 0.000016 |
|
CNVp=CNV/ICV (x 100%) rage(p) |
0.47 ± 0.04 −0.38 (0.03) |
0.41 ± 0.08 −0.29 (0.11) |
0.0006 0.70 |
|
FA @ CNV rage(p) |
0.139 ± 0.011 0.52 (0.003) |
0.152 ± 0.017 0.28 (0.12) |
0.001 0.28 |
|
Dav (x10−3 mm2 sec−1) @ CNV rage(p) |
0.736 ± 0.023 0.16 (0.38) |
0.751 ± 0.031 −0.32 (0.07) |
0.02 0.06 |
|
T2. (msec) @ CNV rage(p) |
91.8 ± 5.2 0.16 (0.37) |
89.4 ± 4.9 0.09 (0.61) |
0.05 0.79 |