Table 4.
Summary of correlation coefficient and its significance {r(p)} between demographic, clinical, whole brain, and caudate nuclei metrics on the RRMS patient group.
| DD | EDSS | WBLVp | WBCSFp | CNVp | FA(CN) | Dav(CN) | T2(CN) | |
|---|---|---|---|---|---|---|---|---|
| Age | 0.365 | 0.074 | 0.036 | 0.291 | −0.291 | 0.296 | −0.322 | 0.094 |
| (0.04) | (0.69) | (0.84) | (0.11) | (0.11) | (0.12) | (0.07) | (0.61) | |
| DD | 1 | 0.189 | 0.207 | 0.224 | −0.24 | 0.296 | −0.161 | 0.205 |
| (0.30) | (0.255) | (0.22) | (0.19) | (0.1) | (0.38) | (0.261) | ||
| EDSS | 1 | 0.299 | 0.362 | −0.143 | 0.078 | 0.311 | 0.311 | |
| (0.097) | (0.04) | (0.43) | (0.67) | (0.08) | (0.084) | |||
| WBLVp | 1 | 0.510 | −0.482 | 0.625 | −0.097 | 0.156 | ||
| (0.003) | (0.005) | (0.0001) | (0.60) | (0.40) | ||||
| WBCSFp | 1 | −0.457 | 0.337 | −0.089 | 0.122 | |||
| (0.01) | (0.06) | (0.63) | (0.51) | |||||
| CNVp | 1 | −0.674 | 0.439 | 0.056 | ||||
| (0.00002) | (0.01) | (0.76) | ||||||
| FA(CN) | 1 | −0.344 | 0.031 | |||||
| (0.05) | (0.866) | |||||||
| Dav(CN) | 1 | 0.119 | ||||||
| (0.52) | ||||||||
Bolded values correspond to statistically significant p-values (p ≤ = 0.05). Examples to help read this Table: r(DD, DD) = 1 (p = 0); Pearson r(age, DD) = r(DD, age) = 0.365 (p = 0.04); Spearman r(age, EDSS) = 0.074 (p = 0.69)}. The mean and SD values (µ ± σ) values for all variables on the RRMS patients are summarized in Table 2 and Table 3. The slope (β) for each variable (y) regressed against another variable (x) can be related to r: slope b = r * σ(y)/σ(x) (linear regression model: y= b * x + a + noise).