TABLE 3.

Blood lactate, alanine, β-hydroxybutyrate, NEFA, and glycerol levels during day 2 exercise euglycemic clamp studies after two 120-min euglycemic clamps (anteEugly), hypoglycemic clamps (anteHypo), or euglycemic clamps with intravenous cortisol infusions of 1 μg · kg⁻¹ · min⁻¹ (anteCort1) or 2 μg · kg⁻¹ · min⁻¹ (anteCort2) on day 1

	Basal period	Final 30 min of exercise
Lactate (mmol/l)
anteEugly	0.8 ± 0.1	1.9 ± 0.2*
anteHypo	0.8 ± 0.1	1.3 ± 0.1*†
anteCort1	0.7 ± 0.1	1.1 ± 0.2*†
anteCort2	0.9 ± 0.1	1.9 ± 0.1*
Alanine (μmol/l)
anteEugly	329 ± 34	418 ± 43*
anteHypo	330 ± 32	367 ± 30*
anteCort1	310 ± 60	360 ± 40*
anteCort2	378 ± 32	419 ± 29*
β-hydroxybutyrate (μmol/l)
anteEugly	40 ± 10	61 ± 10*
anteHypo	48 ± 13	66 ± 18
anteCort1	37 ± 5	51 ± 10
anteCort2	50 ± 10	40 ± 10†
NEFA (μmol/l)
anteEugly	143 ± 25	383 ± 72*
anteHypo	227 ± 42‡	298 ± 48†
anteCort1	148 ± 21	219 ± 61†
anteCort2	149 ± 28	199 ± 39†
Glycerol (μmol/l)
anteEugly	44 ± 9	145 ± 18*
anteHypo	48 ± 10	111 ± 16*†
anteCort1	77 ± 20	111 ± 21*†
anteCort2	50 ± 13	100 ± 14*†

Data are means ± SEM. n = 22 type 1 diabetic subjects (11 men/11 women).

*Significant difference versus basal level (P < 0.05).

†Significantly reduced versus anteEugly (P < 0.05).

‡Significantly increased compared with other groups (P < 0.05).