Table 1.
Subtype C |
Subtype A |
|||||
---|---|---|---|---|---|---|
Sequence | n | % | Sequence | n | % | |
B42− | TPQDLNTML | 36 | 90.0 | TPQDLNMML | 30 | 75.0 |
B81− | ------S-- | 2 | 5.0 | I-------- | 2 | 5 |
--S---S-- | 1 | 2.5 | --G------ | 2 | 5 | |
--A------ | 1 | 2.5 | ------V-- | 2 | 5 | |
------T-- | 1 | 2.5 | ||||
--S------ | 1 | 2.5 | ||||
--H------ | 1 | 2.5 | ||||
I-H------ | 1 | 2.5 | ||||
B81+ | TPQDLNTML | 1 | 14.3 | TPQDLNMML | 8 | 88.9 |
------S-- | 4 | 57.1 | --G------ | 1 | 11.1 | |
--S---S-- | 2 | 28.6 | ||||
B42+ | TPQDLNTML | 6 | 42.9 | TPQDLNMML | 8 | 66.7 |
--T------ | 4 | 28.6 | ------T-- | 2 | 16.7 | |
--S---S-- | 2 | 14.3 | --S------ | 1 | 8.3 | |
--A------ | 1 | 7.1 | I-------- | 1 | 8.3 | |
--G------ | 1 | 7.1 |
Shown are plasma virus TL9 epitope sequences isolated from 122 HIV-infected East Africans from Kenya and Tanzania. The TL9 epitope sequences are grouped into either subtype A or subtype C and then further subdivided according to the presence or absence of the TL9-presenting HLA class I molecules B42 and B81 in the infected host.