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. 2009 Jun 19;114(8):1553–1562. doi: 10.1182/blood-2009-02-206193

Table 1.

HLA class I–associated polymorphisms within the TL9 epitope are observed in subtype C but not in subtype A viruses

Subtype C
Subtype A
Sequence n % Sequence n %
B42 TPQDLNTML 36 90.0 TPQDLNMML 30 75.0
B81 ------S-- 2 5.0 I-------- 2 5
--S---S-- 1 2.5 --G------ 2 5
--A------ 1 2.5 ------V-- 2 5
------T-- 1 2.5
--S------ 1 2.5
--H------ 1 2.5
I-H------ 1 2.5
B81+ TPQDLNTML 1 14.3 TPQDLNMML 8 88.9
------S-- 4 57.1 --G------ 1 11.1
--S---S-- 2 28.6
B42+ TPQDLNTML 6 42.9 TPQDLNMML 8 66.7
--T------ 4 28.6 ------T-- 2 16.7
--S---S-- 2 14.3 --S------ 1 8.3
--A------ 1 7.1 I-------- 1 8.3
--G------ 1 7.1

Shown are plasma virus TL9 epitope sequences isolated from 122 HIV-infected East Africans from Kenya and Tanzania. The TL9 epitope sequences are grouped into either subtype A or subtype C and then further subdivided according to the presence or absence of the TL9-presenting HLA class I molecules B42 and B81 in the infected host.