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No effect of HpTx-2 on KV currents in KChIP2-/- myocytes. A, Representative baseline KV currents recorded using 400-ms pulses from VH=-70 mV to Vstep between -40 and +50 mV (inset) in myocytes from WT and KChIP2-/- mice. Arrowheads indicate 0 pA. B, Currents recorded in the same myocytes after addition of 1 μM HpTx-2 to the superfusion solution. C, The HpTx-2-sensitive currents obtained by digital offline subtraction of the current traces shown in A and B.
