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. Author manuscript; available in PMC: 2009 Aug 25.
Published in final edited form as: J Stroke Cerebrovasc Dis. 2008;17(3):147–152. doi: 10.1016/j.jstrokecerebrovasdis.2008.01.009

Table 3.

Unadjusted analysis of admission serum direct bilirubin versus severe stroke (National Institutes of Health Stroke Scale score >12)

Variable Beta estimate Odds ratio Confidence interval P value
Age 0.002 1.002 0.987–1.017 .772
Female 0.312 1.366 0.876–2.130 .169
Serum glucose (per 1-mg/dL increase) 0.006 1.006 1.002–1.010 .002
Nonsmoker*
Ex-smoker −0.377 0.686 0.406–1.157 .158
Current smoker 0.300 1.349 0.689–2.642 .382
Prior antithrombotic use −0.632 0.531 0.333–0.849 .008
Prior statin use −0.199 0.820 0.485–1.386 .458
History of hypertension 0.624 1.866 1.118–3.115 .017
History of diabetes −0.315 0.730 0.411–1.296 .283
History of hyperlipidemia −0.142 0.868 0.520–1.447 .587
History of atrial fibrillation 0.928 2.530 1.519–4.215 <.001
Premorbid modified Rankin score (< 1)*
Premorbid modified Rankin score = 1 −0.174 0.840 0.454–1.556 .580
Premorbid modified Rankin score = 2 −0.670 0.512 0.156–1.676 .268
Premorbid modified Rankin score = 3 −0.571 0.565 0.151–2.117 .397
Premorbid modified Rankin score = 4–5 1.517 4.556 1.492–13.916 .008
Serum direct bilirubin (≤mg/dL)*
Serum direct bilirubin (0.2 mg/dL) 0.323 1.382 0.863–2.213 .179
Serum direct bilirubin (0.3 mg/dL) 0.250 1.284 0.619–2.665 .502
Serum direct bilirubin (≥mg/dL) 1.024 2.785 1.25–6.202 .012
*

Reference group