Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Reagents and conditions: a, LDA, THF, I2, -78 °C, 3h, 58%; b, 33% NH2Me, EtOH, rt, 1.5h, 94%; c, SOCI2, pyridine, reflux, 3h, 80%; d, i, TFA:H2O (2:1), rt, 18h; ii. Ac2O, pyridine, DMAP, CH2CI2, 12h, 82% for 2 steps; e, 10:1 CH3CN:H2O, CAN, 55 °C, 3h, 86%; f NH3, MeOH, rt, 15h, 65%.
