 | ||
| Entry | R= | Results |
| 5a | Bz | Iodination at multiple sites, including the Bz group |
| 5b | Bn | Removal of Bn problematic; NR to very low yielding, to complete loss of the thiazole ring |
| 5c | BOM | Removal of BOM problematic; results ranged from NR, conversion of the BOM group to Me, which proved intractable to removal |
| 5d | PMB | Removal of the PMB resulted in the loss of the isopropylidine protecting group, and a complex, inseparable product mixture |
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