Table 8.
Levels of BHB associated with AC-1202, fasting, and dietary regimens
| Intervention |
Average BHB levels, mM |
Notes | Reference |
| 12 hour fast | 0.08 – 0.1 | Fasting level on typical diet | This study, [47,48] |
| AC-1202 (20 grams) | 0.36 | 2 hour post-dose levels | This study |
| Low carbohydrate diet | 0.4 – 0.65 | Low carbohydrate diets ranging from 4–10% carbohydrate | [45-48] |
| Ketogenic diet | 0.3 – 1.6 | Ketogenic diets given to children with refractive epilepsy | [49,50] |
| Starvation | 4 – 8 | 5–6 weeks of complete starvation | [51] |
| Diabetic ketoacidosis | 9 – 10 | Insulin deficiency and elevated levels of counter-regulatory hormones | [52] |