Figure 2.
The PAI1 4G/5G SNP is not associated with overall survival or tumoral PAI1 mRNA expression in breast cancer. Kaplan-Meier survival curves for the putative high expression 4G4G (black), intermediate expression 4G5G (dark gray), and low expression 5G5G (light gray) genotypes for all outcome-informative SEARCH (A) and UCSF (B) patients. Mean tumoral PAI1 mRNA expression levels obtained by microarray expression profiling in a subset of UCSF cases for the corresponding PAI1 genotypes (C). Two-tailed log-rank test for trend (A and B) and ANOVA (C) Ps are provided.