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. Author manuscript; available in PMC: 2009 Aug 25.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2006 Nov;15(11):2107–2114. doi: 10.1158/1055-9965.EPI-06-0351

Table 3. PAI1 4G/5G and TGFB1 L10P genotypic distributions in East Anglian women with and without invasive breast cancer.

D PAI1genotype TGFB1Genotype Cases Controls Genotypic odds ratio
(95% confidence interval)		 Additive odds ratio
(95% confidence interval)
0 5G5G LL 161 127 1.00 (reference) graphic file with name nihms75387t1.jpg 1.00 (reference)
1 5G5G LP 204 153 1.05 (0.77-1.44) 1.02 (0.78-1.33)
1 4G5G LL 356 281 1.00 (0.76-1.32)
2 5G5G PP 58 42 1.09 (0.69-1.73) 1.11 (0.86-1.43)
2 4G5G LP 487 362 1.06 (0.81-1.39)
2 4G4G LL 266 174 1.21 (0.89-1.63)
3 4G5G PP 170 104 1.29 (0.92-1.81) 1.07 (0.81-1.41)
3 4G4G LP 271 221 0.97 (0.72-1.30)
4 4G4G PP 101 64 1.24 (0.84-1.84) 1.24 (0.84-1.84)

NOTE: D = dose of putative high-risk alleles. Additive odds ratios were determined for each combined allelic dosage group relative to the reference 5G5G/LL participants who had no putative high-risk alleles.