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. Author manuscript; available in PMC: 2009 Aug 25.
Published in final edited form as: J Biomater Sci Polym Ed. 2008;19(10):1279–1293. doi: 10.1163/156856208786052380

Figure 4.

Figure 4

Gene expression of integrins α1 (A and D), β1 (B and E) and β3 (C and F) over the course of a 7-day culture period. RT-PCR results were normalized to GAPDH expression for each geometry and matrix condition, and are shown relative to 3D collagen day 1. Data from day 3 only are shown in panels A-C, while panels D-F show gene expression over time. Two matrix geometries were used two-dimensional monolayer (2D) and three-dimensional matrices (3D). The matrix materials used were tissue-culture plastic (TCP), collagen (C), collagen-fibrin (CF) and fibrin (F). The effects of matrix geometry are shown in panels A-C and the effects of composition and time in TCP and 3D systems are shown in panels D-F. Results are expressed as the mean ± SEM.