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Simultaneous measurement of PaO2, O2 depletion rate (ODR), and ADC with HP 3He MRI in a patient with COPD. In the selected region, ADC value is 29% higher while ODR value is 61% lower than the corresponding global average values. This correlated change can be representative of the lung tissue destruction with gas exchange deficiency. The missing lobe on the upper portion of the right lung is indicative of a substantial ventilation defect. Reprinted by permission from Reference 29.
