Table 1. In vivo confocal microscopy scoring for the evaluation of ocular toxicity in CALT analysis.

CALT reactivity is evaluated in two different areas: inside and outside the follicle
Inflammatory cell infiltration score	Inflammatory cells/mm2
0/1	0–100
2	100–500
3	500–1000
4	>1000

For IVCM-CALT analysis, we took into account the level of inflammatory cell infiltration at the periphery (outside) and in the center (inside) of the superficial layers in CALT follicles: (0/1): no or very slight infiltration (0–100 inflammatory cells/mm²); (2): moderate (100–500 inflammatory cells/mm²); (3): pronounced (500–1000 inflammatory cells/mm²), (4): severe (>1000 inflammatory cells/mm²).