Figure 6.

BPh interactions conserved between E. coli and T. thermophilus rRNA 3D structures mapped on the 2D structure of E. coli 16S rRNA (46). Red symbols were used to denote the edge used by each base donor (circle for Watson–Crick edge, square for Hoogsteen edge, triangle for Sugar edge and diamond for the Adenine 2BPh which straddles the WC and Sugar edges). The 1BPh interactions that are conserved at the base pair level, are marked by red triangles placed between the bases forming the WC base pair. Green circles denote the locations of phosphate acceptors.