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Mean group total distance traveled scores (cm) for rats treated with 0, 1.0, 2.0 and 4.0 mg/kg METH starting on Day 11. The control and lead-pretreated groups (n=8 per group) in this panel were treated on Days 1–10 with either vehicle or 1.0 mg/kg METH. The bar above each symbol reflects the standard error of the mean for that value. Significant differences (p < 0.05) between rats pretreated with VEH and rats pretreated with METH are denoted by a *.
