TABLE 5.
Validation of gene expression by qRT-PCR
| Symbol | Fold change | SAM rank | P-value (≤0.05) |
|---|---|---|---|
| BPH versus TZ | |||
| SULF1 | ↓5.1 | ↓1 | Yes |
| TGFB2 | ↓1.4 | ↓2 | No |
| LASS6 | ↓5.1 | ↓3 | Yes |
| S100A4 | ↑9.3 | ↑1 | Yes |
| TOX | ↑5.5 | ↑2 | Yes |
| BUB1 | ↑3.4 | ↑3 | No |
| CLDN23 | ↑4.6 | ↑7 | Yes |
| OAS2 | ↑2.0 | ↑8 | No |
| IF | ↑5.3 | ↑9 | Yes |
| GBP2 | ↑11.6 | ↑11 | Yes |
| DNAJC4 | ↑1.1 | ↑12 | No |
| GLI3 | ↑9.4 | ↑13 | Yes |
| S100A10 | ↑5.5 | ↑17 | Yes |
| BST1 | ↑1.4 | ↑28 | No |
| BPH versus CA | |||
| SULF1 | ↓4.6 | ↓2 | No |
| OGN | ↓10.0 | ↓3 | Yes |
| THY1 | ↓3.8 | ↓6 | Yes |
| BST1 | ↑3.3 | ↑1 | Yes |
| TOX | ↑3.4 | ↑6 | Yes |
| IGF-2 | ↑9.9 | ↑7 | Yes |
| LOC492304 | ↑9.6 | ↑12 | Yes |
| CA versus PZ | |||
| ENPP2 | ↑2.7 | ↑1 | Yes |
| TM4SF3 | ↑8.3 | ↑2 | Yes |
| SEPT6 | ↑3.5 | ↑6 | Yes |
| ICAM4 | ↑2.7 | ↑8 | Yes |
| LOC91431 | 1.0 | ↑12 | No |
| ADCK1 | ↓1.4 | ↑13 | No |
| DLL3 | ↓1.4 | ↑15 | No |
| WDR7 | ↑1.5 | ↑23 | Yes |
| IGF-1 | ↑2.7 | ↑32 | No |
| BCL2A1 | ↑9.4 | ↑34 | No |
| FRAG1 | ↓1.1 | ↑37 | No |
| FGFR1 | ↑2.0 | ↑78 | Yes |
| OGN | ↑5.8 | ↑88 | Yes |
| PON1 | ↓2.0 | ↑100 | No |