Table 3.
Multivariable risk factor analysis for presence of Descending Thoracic calcification and Coronary Calcium.
DTAC | CAC | |||||
---|---|---|---|---|---|---|
Variable | PR | 95% CI | p-value | PR | 95% CI | p-value |
Age (per 10 yr) | 1.99 | 1.92, 2.06 | <0.001 | 1.37 | 1.34, 1.40 | <0.001 |
Gender (Female vs Male) | 0.87 | 0.82, 0.94 | <0.001 | 1.38 | 1.32, 1.44 | <0.001 |
Race | ||||||
White | 1.00 (ref) | -- | -- | 1.00 (ref) | -- | -- |
Chinese | 1.05 | 0.96, 1.16 | 0.272 | 0.93 | 0.86, 1.00 | 0.049 |
African-American | 0.65 | 0.59, 0.74 | <0.001 | 0.76 | 0.72, 0.80 | <0.001 |
Hispanic | 0.83 | 0.77, 0.91 | <0.001 | 0.84 | 0.80, 0.89 | <0.001 |
Former smoker | 1.10 | 1.03, 1.17 | 0.003 | 1.11 | 1.06, 1.16 | <0.001 |
Current smoker | 1.44 | 1.30, 1.60 | <0.001 | 1.24 | 1.16, 1.32 | <0.001 |
BMI (per SD=5.5) | 0.96 | 0.93, 1.00 | 0.062 | 1.04 | 1.02, 1.07 | <0.001 |
Hypertension | 1.35 | 1.26, 1.46 | <0.001 | 1.14 | 1.09, 1.19 | <0.001 |
Diabetes | 1.09 | 1.00, 1.18 | 0.048 | 1.11 | 1.05, 1.17 | <0.001 |
Family history of heart attack | 1.10 | 1.03, 1.17 | 0.003 | 1.16 | 1.11, 1.21 | <0.001 |
LDL (per SD=31) | 1.06 | 1.03, 1.10 | <0.001 | 1.07 | 1.05, 1.09 | <0.001 |
HDL (per SD=15) | 0.95 | 0.91, 0.94 | 0.005 | 0.96 | 0.94, 0.99 | 0.004 |
Lipid lowering meds | 1.15 | 1.07, 1.23 | <0.001 | 1.18 | 1.12, 1.23 | <0.001 |
CRP (per SD=5.89) | 1.00 | 0.97, 1.03 | 0.986 | 1.00 | 0.97, 1.02 | 0.683 |
Interleukin-6 (per SD=1.22) | 1.03 | 1.00, 1.06 | 0.067 | 1.02 | 0.99, 1.04 | 0.074 |
Fibrinogen (per SD=74) | 1.04 | 1.01, 1.08 | 0.023 | 1.03 | 1.01, 1.05 | 0.007 |
Factor VIII (per SD=67) | 1.00 | 0.97, 1.03 | 0.909 | 1.03 | 1.01, 1.05 | 0.002 |
(all variables were entered into the model simultaneously)
BMI = body mass index; CAC = coronary artery calcium; CRP = C reactive protein; DTAC = descending thoracic aortic calcification; HDL = high density lipoprotein; LDL = low density lipoprotein; SD = standard deviation