Table 1. Meta-COPA analysis of 7 prostate cancer gene expression profiling datasets in Oncomine.
Genes were ranked by the number of studies in which they scored in the top 100 outliers (ranked by COPA) at any of the three pre-defined percentile cutoffs (75th, 90th, 95th). Genes were further ranked by their average COPA rank (Avg. Rank) in studies where they ranked in the top 100. ETS genes are indicated in bold. Genes showing outlier-expression exclusively in prostate cancer and mutually exclusive outlier expression with ETS genes are indicated in bold italics. Genes showing outlierexpression in benign prostate tissue are indicated by asteriks. Genes without mutual exclusivity with ERG or ETV1 outlier expression are indicated by italics.
| Meta COPA Rank | Gene | # of Studies | Avg. Rank |
|---|---|---|---|
| 1 | ERG | 7 | 19.3 |
| 2 | SPINK1 | 5 | 29.8 |
| 3 | GPR116 | 5 | 46 |
| 4 | ORM1* | 4 | 10 |
| 5 | ETV1 | 4 | 23 |
| 6 | MYL2* | 4 | 26.8 |
| 7 | NEB* | 4 | 27 |
| 8 | TGM4* | 4 | 30.8 |
| 9 | NELL2* | 4 | 33.5 |
| 10 | KRT13* | 4 | 49 |
| 11 | SLC26A4* | 4 | 63.3 |