Table 2.
FV3 gene expression in the presence of CHX
| FV3 ORF or host gene Acc. No. |
Gene name | Fold Upregulation a |
|---|---|---|
| orf12L | Unknown | 4.5 |
| orf14R | Unknown | 3.07 |
| orf23R | Unknown | 5.53 |
| orf24R | Unknown | 5.4 |
| orf29L | Unknown | 3.83 |
| orf32R | Neurofilament triplet H1-like protein | 1.63 |
| orf33R | Unknown | 5.07 |
| orf35L | Unknown | 2.24 |
| orf36L | Unknown | 2.07 |
| orf39R | Hydrolase of the metallo-beta-lactamase superfamily | 1.95 |
| orf42L | Unknown | 5.28 |
| orf43R | Unknown | 2.41 |
| orf44R | Unknown | 4.33 |
| orf46L | Neurofilament triplet H1-like protein | 4.62 |
| orf47L | Unknown | 3.69 |
| orf49L | SAP DNA binding domain | 4.87 |
| orf56R | Unknown | 5.23 |
| orf57R | Serine/threonine protein kinase | 1.51 |
| orf58R | Unknown | 4.42 |
| orf61L | Unknown | 2.88 |
| orf63R | dUTPase | 2.72 |
| orf64R | vCARD | 1.77 |
| orf66L | Unknown | 2.51 |
| orf67L | RR β | 5.64 |
| orf71R | Unknown | 2.69 |
| orf72L | Unknown | 2.85 |
| orf73L | NTPase/helicase-like protein | 6.8 |
| orf82R | ICP-18 (18K) | 94.99 |
| orf84R | Proliferating cell nuclear antigen (PCNA) | 3.36 |
| orf89R | Unknown | 1.51 |
| orf91R | ICP-46 | 12.59 |
| orf92R | Unknown | 1.54 |
| orf93L | Unknown | 6.66 |
| orf94L | P8.141C-like protein | 3.1 |
| orf96R | Unknown | 9.52 |
| orf97R | MCL-1 region | 1.93 |
| orf98R | Unknown | 2.03 |
a
Fold upregulation (i.e., normalized log ratios) was derived from the average of three independent experiments in which expression levels of genes transcribed in the presence of CHX were compared to those transcribed in its absence. Genes upregulated in the presence of CHX >1.5 fold with p values <0.05 are listed in the table.