Table 3.
Gene expression in cells infected with ts5 at non-permissive temperatures.
| Host Gene Acc. No. or FV3 ORF |
Gene name | Fold Upregulation |
|---|---|---|
| orf5R | Orf250-like protein | 2.12 |
| orf6R | Unknown | 1.87 |
| orf13R | Unknown | 2.30 |
| orf14R | Unknown | 2.53 |
| orf19R | Uncharacterized conserved protein | 1.92 |
| orf22R | D5 family NTPase/ATPase | 1.62 |
| orf23R | Unknown | 5.58 |
| orf24R | Unknown | 1.68 |
| orf25R | p31K protein | 3.07 |
| orf30R | Unknown | 1.51 |
| orf38R | RR α | 3.16 |
| orf39R | Hydrolase of the metallo-beta-lactamase superfamily | 1.57 |
| orf46L | Neurofilament triplet H1-like protein | 8.62 |
| orf47L | Unknown | 2.19 |
| orf49L | SAP DNA binding domain | 4.44 |
| orf50L | Unknown | 4.32 |
| orf52L | 3-beta-hydroxy steroid oxidoreductase (β HSD) | 1.83 |
| orf53R | Orf20-like protein | 1.60 |
| orf54L | Nuclear calmodulin-binding protein | 1.96 |
| orf57R | Serine/threonine protein kinase | 1.85 |
| orf60R | DNA polymerase family B | 1.64 |
| orf61L | Unknown | 2.39 |
| orf64R | vCARD | 2.14 |
| orf67L | RR β | 1.85 |
| orf70R | Unknown | 1.71 |
| orf77L | Unknown | 2.48 |
| orf78L | ATPase-dependent protease | 1.95 |
| orf80L | Ribonuclease III (RNase III) | 1.66 |
| orf81R | Transcriptional elongation factor IIS | 4.11 |
| orf82R | ICP-18 (18K) | 3.30 |
| orf85R | Deoxynucleoside kinase | 2.68 |
| orf89R | Unknown | 2.55 |
| orf91R | ICP-46 | 2.30 |
| orf92R | Unknown | 1.75 |
| orf94L | P8.141C-like protein | 2.01 |
| orf95R | DNA repair protein RAD2 | 2.80 |
| orf98R | Unknown | 10.78 |
Fold upregulation (i.e., normalized log ratios) was calculated from the average of three independent experiments in which expression levels of genes transcribed at 30°C (non-permissive temperature) were divided by the average expression of the same genes transcribed at 25°C (permissive conditions). Genes upregulated in ts5-infected cells >1.5 fold (p values <0.05) at 30°C are listed in the table.