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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Curr Opin Infect Dis. 2008 Oct;21(5):468–475. doi: 10.1097/QCO.0b013e32830ef5cf

Figure 3.

Figure 3

Relationships of malaria disease severity to nitric oxide, endothelial function, and clinical parameters in Indonesian adults gr3

Indonesian adults were evaluated for parasitemia, plasma arginine, plasma arginase, plasma lactate, reactive hyperemia peripheral artery tonometry (RH PAT), and exhaled nitric oxide (NO) levels on presentation to the hospital. Healthy control adults (HC), those with moderately severe malaria (MSM), and those with severe malaria (SM) were assessed. The units of measure in this figure were normalized for purposes of presentation clarity; the measures do not represent the actual absolute values for the different parameters. With increasing malaria disease severity, there were progressive increases in parasitemia, arginase, and lactate (left panel) fx1 Arginase; fx2 lactate; fx3 parasitemia. However, with increasing disease severity, plasma arginine, RH PAT, and exhaled NO generally decreased (right panel) fx1 Arginine; fx2 RH PAT; fx3 exhaled NO. This figure was constructed from data from Yeo et al. [28••].