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. 2009 Jun 5;32(9):1577–1582. doi: 10.2337/dc09-0395

Figure 1.

Figure 1

A: Mean changes in insulin dosage over the course of the trial. Solid squares, unbroken line = basal insulin in the pramlintide group. Open triangles, unbroken line = basal insulin in the RAIA group. Open circles, broken line = total insulin (basal plus mealtime) in the RAIA group. B: Mean A1C at each visit. Solid squares = pramlintide; open circles = RAIA. C: Least squares mean weight changes over time with the last observation carried forward. Solid squares = pramlintide; open circles = RAIA. ***P < 0.001; **P < 0.01. D: Mean fasting plasma glucose over time. Solid squares = pramlintide; open circles = RAIA. LOCF, last observation carried forward; LS, least squares.