Table 4.

Three most significant gene sets identified by SPCA method for females and males, among gene sets with significant Sex × PC1 interaction

GO term	Size	Description	Adj P-value
Females
0007242	265	intracellular signaling cascade	0.0999
0006511	105	ubiquitin-dependent protein catabolic process	0.0999
0009117	24	nucleotide metabolic process	0.0999
Males
0019882	29	antigen processing and presentation	0.0802
0006811	161	ion transport	0.0802
0045449	219	regulation of transcription	0.0802