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. 2008 Nov 5;25(1):75–82. doi: 10.1093/bioinformatics/btn577

Table 2.

SPIA results on colorectal cancer dataset

KEGG pathway PNDE PPERT PG PFDRa PFWERb Status
Focal adhe..4510 0.0001 0.0000 0.0000 0.00000 0.00000 Act.
ECM-recept..4512 0.0001 0.0004 0.0000 0.00001 0.00002 Act.
PPAR signa..3320 0.0000 0.1240 0.0000 0.00011 0.00034 Inh.
Alzheimers..5010 0.0000 0.7260 0.0001 0.00059 0.00235 Act.
Adherens j..4520 0.0001 0.0852 0.0001 0.00090 0.00452 Act.
Axon guida..4360 0.0002 0.2324 0.0006 0.00487 0.02922 Act.
MAPK signa..4010 0.0001 0.7112 0.0007 0.00504 0.03527 Inh.
Tight junc..4530 0.0007 0.5156 0.0032 0.02073 0.16585 Act.
Colorectal..5210 0.0098 0.0432 0.0037 0.02151 0.19359 Act.
Wnt signal..4310 0.0187 0.0704 0.0101 0.05227 0.52268 Inh.
Renal cell..5211 0.0259 0.1048 0.0188 0.08869 0.97561 Inh.
Regulation..4810 0.0046 0.7328 0.0226 0.09797 1.00000 Act.
Thyroid ca..5216 0.0516 0.1032 0.0332 0.13284 1.00000 Inh.
Cytokine-c..4060 0.5049 0.0132 0.0401 0.14880 1.00000 Act.
Antigen pr..4612 0.9948 0.0080 0.0464 0.16094 1.00000 Act.

abCalculated for PG; Act., activated, Inh., inhibited. The last pathway considered significant is underlined (FDR<0.05).