Table 2.
SPIA results on colorectal cancer dataset
KEGG pathway | PNDE | PPERT | PG | PFDRa | PFWERb | Status |
---|---|---|---|---|---|---|
Focal adhe..4510 | 0.0001 | 0.0000 | 0.0000 | 0.00000 | 0.00000 | Act. |
ECM-recept..4512 | 0.0001 | 0.0004 | 0.0000 | 0.00001 | 0.00002 | Act. |
PPAR signa..3320 | 0.0000 | 0.1240 | 0.0000 | 0.00011 | 0.00034 | Inh. |
Alzheimers..5010 | 0.0000 | 0.7260 | 0.0001 | 0.00059 | 0.00235 | Act. |
Adherens j..4520 | 0.0001 | 0.0852 | 0.0001 | 0.00090 | 0.00452 | Act. |
Axon guida..4360 | 0.0002 | 0.2324 | 0.0006 | 0.00487 | 0.02922 | Act. |
MAPK signa..4010 | 0.0001 | 0.7112 | 0.0007 | 0.00504 | 0.03527 | Inh. |
Tight junc..4530 | 0.0007 | 0.5156 | 0.0032 | 0.02073 | 0.16585 | Act. |
Colorectal..5210 | 0.0098 | 0.0432 | 0.0037 | 0.02151 | 0.19359 | Act. |
Wnt signal..4310 | 0.0187 | 0.0704 | 0.0101 | 0.05227 | 0.52268 | Inh. |
Renal cell..5211 | 0.0259 | 0.1048 | 0.0188 | 0.08869 | 0.97561 | Inh. |
Regulation..4810 | 0.0046 | 0.7328 | 0.0226 | 0.09797 | 1.00000 | Act. |
Thyroid ca..5216 | 0.0516 | 0.1032 | 0.0332 | 0.13284 | 1.00000 | Inh. |
Cytokine-c..4060 | 0.5049 | 0.0132 | 0.0401 | 0.14880 | 1.00000 | Act. |
Antigen pr..4612 | 0.9948 | 0.0080 | 0.0464 | 0.16094 | 1.00000 | Act. |
abCalculated for PG; Act., activated, Inh., inhibited. The last pathway considered significant is underlined (FDR<0.05).