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. 2009 May 4;25(13):1587–1593. doi: 10.1093/bioinformatics/btp273

Table 2.

Cross species ranks —this table shows the results of aligning the cDNAs of mouse, rat and humans to the mouse genome

Aligner Mouse Rank Rat Rank Human Rank
Blat 97.23 6 71.29 18 43.79 17
BlatX 95.21 13 35.7 22 9.27 22
Est2Genome 94.38 15 85.14 10 75.67 9
Est2Genome+ 95.15 14 76.22 15 56.63 14
Exalin 97.3 5 87.77 7 78.11 7
Exonerate 95.5 12 85.17 9 63.57 10
ExonerateCG 96.42 10 84.26 12 59.05 13
ExonerateDG 96.16 11 84.36 11 59.78 12
GeneSeqer 74.81 21 64.28 19 50.33 16
GMap 93.13 16 82.39 13 60.74 11
Pairagon 98.88 1 91.59 2 77.04 8
PairagonX 98.79 2 92.15 1 87.24 1
Palma 96.52 9 77.8 14 33.28 20
Sim4 91.94 19 76.03 16 35.48 18
Sim4+ 92.5 18 75.49 17 35.05 19
Spaln 97.51 3 90.11 4 82.68 5
SpalnX 96.89 8 90.09 5 86.67 2
Spidey 88.53 20 48.05 21 13.1 21
SpideyX 70.1 22 61.7 20 52.94 15
Splign 97.46 4 90.21 3 82.94 4
SplignX 97.19 7 89.88 6 86.1 3
Xat 92.78 17 85.59 8 79.19 6

For each aligner, we show the product of exon specificity and sensitivity (as in Fig. 3) and the rank of the aligner, which shows which aligners were the most accurate.

HHS Vulnerability Disclosure