Table 6.
Correlations with FAa | Hemisphere | Talairach and Tournoux coordinates (peak voxel) |
Peak Z score (ID/AO) | No. of voxels (ID/AO) | P | ||
---|---|---|---|---|---|---|---|
White matter tract/region | x | y | z | ||||
Prefrontal white matter (forceps minor, anterior thalamic radiation) | Right | 12 | 50 | 8 | 3.66/3.62 | 103/109 | < 0.001 |
Superior frontal white matter | Left | −21 | 8 | 32 | 3.67/3.69 | 177/184 | < 0.001 |
External capsule | Left | −27 | 2 | 8 | 3.50/3.50 | 60/64 | < 0.001 |
Posterior limb of internal capsule, External capsule | Left | −23 | −28 | 1 | 3.58/3.60 | 345/373 | < 0.001 |
Superior longitudinal fasciculus | Left | −25 | −30 | 35 | 3.25/3.29 | 50/53 | 0.001 |
Correlations with MDb | Hemisphere | Talairach and Tournoux coordinates (peak voxel) |
Peak Z score (ID/AO) | No. of voxels (ID/AO) | P | ||
White matter tract/region | x | y | z | ||||
| |||||||
Superior frontal white matter | Left | −10 | 42 | 34 | 4.53/4.54 | 303/310 | < 0.001 |
Superior frontal white matter (next to dorsal cingulate gyrus) | Right | 4 | 16 | 40 | 4.29/4.36 | 1580/1529 | < 0.001 |
External capsule | Left | −31 | −22 | 7 | 3.96/3.93 | 1723/1510 | < 0.001 |
Superior longitudinal fasciculus | Right | 41 | −25 | 25 | 3.35/3.32 | 60/52 | < 0.001 |
Superior and inferior longitudinal fasciculi | Right | 24 | −57 | 28 | 4.06/4.00 | 511/468 | < 0.001 |
FA, fractional anisotropy; ID, illness duration; AO, age of illness onset
Negative correlation with illness duration and positive correlation with age of illness onset
Positive correlation with illness duration and negative correlation with age of illness onset