. Author manuscript; available in PMC: 2009 Oct 1.

Published in final edited form as: Eur Arch Psychiatry Clin Neurosci. 2009 Mar 3;259(6):316–328. doi: 10.1007/s00406-009-0002-8

Table 6.

Voxelwise correlations between both illness duration and age of illness onset and diffusion imaging variables in BD-I group

Correlations with FA^a	Hemisphere	Talairach and Tournoux coordinates (peak voxel)			Peak Z score (ID/AO)	No. of voxels (ID/AO)	P
White matter tract/region		x	y	z
Prefrontal white matter (forceps minor, anterior thalamic radiation)	Right	12	50	8	3.66/3.62	103/109	< 0.001
Superior frontal white matter	Left	−21	8	32	3.67/3.69	177/184	< 0.001
External capsule	Left	−27	2	8	3.50/3.50	60/64	< 0.001
Posterior limb of internal capsule, External capsule	Left	−23	−28	1	3.58/3.60	345/373	< 0.001
Superior longitudinal fasciculus	Left	−25	−30	35	3.25/3.29	50/53	0.001
Correlations with MD^b	Hemisphere	Talairach and Tournoux coordinates (peak voxel)			Peak Z score (ID/AO)	No. of voxels (ID/AO)	P
White matter tract/region		x	y	z

Superior frontal white matter	Left	−10	42	34	4.53/4.54	303/310	< 0.001
Superior frontal white matter (next to dorsal cingulate gyrus)	Right	4	16	40	4.29/4.36	1580/1529	< 0.001
External capsule	Left	−31	−22	7	3.96/3.93	1723/1510	< 0.001
Superior longitudinal fasciculus	Right	41	−25	25	3.35/3.32	60/52	< 0.001
Superior and inferior longitudinal fasciculi	Right	24	−57	28	4.06/4.00	511/468	< 0.001

FA, fractional anisotropy; ID, illness duration; AO, age of illness onset

Negative correlation with illness duration and positive correlation with age of illness onset

Positive correlation with illness duration and negative correlation with age of illness onset