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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Prostate. 2009 May 1;69(6):571–584. doi: 10.1002/pros.20906

Fig. 1.

Fig. 1

Effects of androgen ablation on levels of serum cytokines and chemokines. Serum was collected from sham-castrated (n=11) and castrated (n=13) C57BL/6 mice three weeks post surgery and a multiplex cytokine assay was carried out to determine whether there were differences in serum cytokine/chemokine levels in castrated compared to sham-castrated mice. A: IL-10, IL-17 and IL-12p70 were statistically significantly reduced in the serum of castrated mice compared to sham-castrated controls. IL-1a and IL-12p40 were statistically significantly increased in the serum of castrated mice compared to sham-castrated controls. B: Serum levels of IL-6, TNFα and IFNγ were not statistically significantly different between castrated mice and sham-castrated controls. Figures are representative of three independent experiments. Data were analyzed using two-tailed t-tests. Abbreviation: ELISA; enzyme-linked immunosorbent assay.