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Identification of modification sites of histone H3. A. MALDI-TOF mass spectrum showing mono- (m/z 718.43), di- (m/z 732.44), tri- (m/z 746.46) methylation at Lysine 4 of histone H3. B. MALDI-TOF mass spectrum showing acetylation (m/z 815.40) at Lysine 14 of histone H3. C. MALDI-TOF mass spectrum showing acetylation (m/z 730.42) at Lysine 18 of histone H3. D. MALDI-TOF mass spectrum showing acetylation (m/z 1028.57) at Lysine 23 of histone H3. Me: methylation; Ac: acetylation.
