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Serologic and genetic characteristics of the patient cohort
| Crohn’s disease (n=252) | Ulcerative colitis (n=53) | HC (n=43) | |
|---|---|---|---|
| Serological Profile (%) | |||
| - A4-Fla2-positive | 59% | 6% | 0% |
| - Fla-X-positive | 57% | 6% | 2% |
| - ASCA-positive | 62% | 4% | 5% |
| - p-ANCA-positive | 12% | 51% | 0% |
| - PAB-positive | 22% | 0% | 0% |
|
| |||
| NOD2 genotype for SNP 8, 12, and 13 (%) | |||
| - No mutations | 64% | 85% | 98% |
| - Heterozygous | 29% | 15% | 2% |
| - Compound heterozygous/homozygous | 7% | 0% | 0% |
Abbreviations: HC, healthy controls
