Table 3.

Antibody responses (in percent) to different microbial antigens and autoantigens in association with distinct disease phenotypes in CD patients

Clinical phenotype		Stricturing		Fistulizing		Inflammatory		Small bowel disease		Small bowel surgery
		Yes	No	Yes	No	Yes	No	Yes	No	Yes	No
A4-Fla2	% Positive	72.5	52.8	72.4	55.5	40.5	71.7	65.7	41.5	71.7	55.9
	P value	0.006		0.029		<0.001		0.002		0.03
Fla-X	% Positive	67.5	52.1	72.4	52.4	38.1	69.6	65.1	37.5	71.7	51.9
	P value	0.023		0.01		<0.001		<0.001		0.01
ASCA	% Positive	85	49.3	75.9	57.3	33.3	79.7	75.9	21.4	83	53.7
	P value	<0.001		0.015		<0.001		<0.001		<0.001
p-ANCA	% Positive	2.5	16.9	13.8	11	19	7.2	7.2	23.2	5	13.6
	P value	0.001		0.566		0.008		0.001		0.072
PAB	% Positive	27.5	20.4	27.6	20.7	15.7	27.8	25.9	13.5	31	19.7
	P value	0.285		0.264		0.039		0.063		0.08
NOD2	% Positive	38.9	34.1	36.8	35.5	32.1	38	40.9	25	43.9	32.5
	P value	0.558		0.883		0.471		0.025		0.104

Abbreviations: Yes, phenotype present; No, phenotype absent