Fig. 4.

The antigen cliques. (A) The normalized antigen correlation matrix of the IgM isotype of 45 antigens that compose the strong cliques in the maternal dataset. (B) Similar to A but for the IgG data. Note that in this case 57 antigens were selected and the IgM and IgG antigen clique members do not have to be similar. (C and D) The corresponding antigen networks. Note that 4 and 3 subgroups were identified for the IgM and IgG isotypes, respectively. In the presentation of the antigen networks, nodes (antigens) with high correlations (>0.85) are linked with color coded lines according to the correlation levels.