Fig. 2.

Structural analysis of the Nup120 NTD domains. (A) Ribbon representation of the Nup120 β propeller domain. The 7 blades of the β propeller core (yellow), the location of the disordered 1E1A loop (orange), the 3D4A loop (red), the α-helical insertion in the 6D7A loop (blue), and their secondary structure elements are indicated. (B) Schematic representation of the Nup120 β propeller domain and the locations of its various insertions. (C) Ribbon representation of the Nup120 α-helical domain. The leucine zipper–like core (orange) and the 9 surrounding α-helices (green) are indicated. A 180°-rotated view is shown on the right.