Table 1.
List of most differentially regulated genes in 4OHT-treated K13 ER-HUVECs.
| Gene Name | Gene | Entrez Gene | Fold Change | |
| Up-regulated genes | ||||
| 1 | chemokine (C-C motif) ligand 2 | CCL2 | 6347 | 71.4 |
| 2 | ubiquitin D | UBD | 10537 | 58.4 |
| 3 | chemokine (C-C motif) ligand 20 | CCL20 | 6364 | 53.1 |
| 4 | chemokine (C-C motif) ligand 5 | CCL5 | 6352 | 48.3 |
| 5 | chemokine (C-X-C motif) ligand 10 | CXCL10 | 3627 | 47.7 |
| 6 | vascular cell adhesion molecule 1 | VCAM1 | 7412 | 46.0 |
| 7 | selectin E (endothelial adhesion molecule 1) | SELE | 6401 | 35.4 |
| 8 | superoxide dismutase 2, mitochondrial | SOD2 | 6648 | 35.2 |
| 9 | chemokine (C-X-C motif) ligand 3 | CXCL3 | 2921 | 33.8 |
| 10 | chemokine (C-X-C motif) ligand 2 | CXCL2 | 2920 | 32.2 |
| 11 | interleukin 8 | IL8 | 3576 | 31.5 |
| 12 | chromosome 15 open reading frame 48 | C15orf48 | 84419 | 29.6 |
| 13 | solute carrier family 7 (cationic amino acid transporter) | SLC7A2 | 6542 | 23.2 |
| 14 | chemokine (C-X3-C motif) ligand 1 | CX3CL1 | 6376 | 22.3 |
| 15 | intercellular adhesion molecule 1 (CD54) | ICAM1 | 3383 | 22.2 |
| 16 | tumor necrosis factor, alpha-induced protein 6 | TNFAIP6 | 7130 | 21.2 |
| 17 | interleukin 6 (interferon, beta 2) | IL6 | 3569 | 21.1 |
| 18 | colony stimulating factor 2 (granulocyte-macrophage) | CSF2 | 1437 | 15.1 |
| 19 | interferon stimulated exonuclease gene 20 kDa | ISG20 | 3669 | 13.6 |
| 20 | chemokine (C-X-C motif) ligand 5 | CXCL5 | 6374 | 13.0 |
| 21 | laminin, gamma 2 | LAMC2 | 3918 | 12.7 |
| 22 | tumor necrosis factor, alpha-induced protein 3 | TNFAIP3 | 7128 | 12.5 |
| 23 | matrix metallopeptidase 10 (stromelysin 2) | MMP10 | 4319 | 11.5 |
| 24 | tumor necrosis factor, alpha-induced protein 2 | TNFAIP2 | 7127 | 11.3 |
| 25 | Epstein-Barr virus induced gene 3 | EBI3 | 10148 | 9.8 |
| 26 | tumor necrosis factor (ligand) superfamily, member 13b | TNFSF13B | 10673 | 9.6 |
| 27 | phospholipase A1 member A | PLA1A | 51365 | 9.4 |
| 28 | GTP cyclohydrolase 1 (dopa-responsive dystonia) | GCH1 | 2643 | 9.0 |
| 29 | nuclear factor of kappa light polypeptide gene enhancer, alpha | NFKBIA | 4792 | 8.3 |
| 30 | proteasome (prosome, macropain) subunit, beta type, 9 | PSMB9 | 5698 | 7.9 |
| 31 | Chemokine (C-X-C motif) 1 | CXCl1 | 2919 | 7.7 |
| 32 | histone cluster 2, H2aa3 | HIST2 | 723790 | 7.5 |
| 33 | HLA-G histocompatibility antigen, class I, G | HLA-G | 3135 | 7.2 |
| 34 | hydroxysteroid (11-beta) dehydrogenase 1 | HSD11B1 | 3290 | 7.2 |
| 35 | chemokine (C-X-C motif) receptor 7 | CXCR7 | 57007 | 7.0 |
| 36 | major histocompatibility complex, class I, B | HLA-B | 3106 | 6.3 |
| 37 | nuclear receptor coactivator 7 | NCOA7 | 135112 | 6.1 |
| 38 | myxovirus (influenza virus) resistance 2 (mouse) | MX2 | 4600 | 5.8 |
| 39 | radical S-adenosyl methionine domain containing 2 | RSAD2 | 91543 | 5.6 |
| 40 | TNFAIP3 interacting protein 1 | TNIP1 | 10318 | 5.5 |
| 41 | tissue factor pathway inhibitor 2 | TFPI2 | 7980 | 5.4 |
| 42 | interleukin 32 | IL32 | 9235 | 5.3 |
| 43 | Nibrin | NBN | 4683 | 5.2 |
| 44 | receptor (chemosensory) transporter protein 4 | RTP4 | 64108 | 5.2 |
| 45 | baculoviral IAP repeat-containing 3 | BIRC3 | 330 | 5.1 |
| 46 | interleukin 7 receptor /// interleukin 7 receptor | IL7R | 3575 | 5.0 |
| 47 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | TAP1 | 6890 | 5.0 |
| 48 | papilin, proteoglycan-like sulfated glycoprotein | PAPLN | 89932 | 4.9 |
| 49 | Major histocompatibility complex, class I, F | HLA-F | 3134 | 4.9 |
| 50 | myosin, light chain kinase | MYLK | 4638 | 4.9 |
| Down-regulated genes | ||||
| 1 | extracellular link domain containing 1 | XLKD1 | 10894 | 11.1 |
| 2 | chemokine (C-C motif) ligand 14 | CCL14 | 6358 | 11.0 |
| 3 | ADAM metallopeptidase with thrombospondin type 1 motif, 18 | ADAMTS18 | 170692 | 7.8 |
| 4 | LIM domain binding 2 | LDB2 | 9079 | 6.7 |
| 5 | keratin 18 | KRT18 | 3875 | 5.3 |
| 6 | dual specificity phosphatase 4 | DUSP4 | 1846 | 5.3 |
| 7 | ribonuclease, RNase A family, 1 (pancreatic) | RNASE1 | 6035 | 4.7 |
| 8 | periostin, osteoblast specific factor | POSTN | 10631 | 4.7 |
| 9 | insulin-like growth factor binding protein 5 | IGFBP5 | 3488 | 4.6 |
| 10 | regulator of G-protein signalling 5 | RGS5 | 8490 | 4.6 |
| 11 | uroplakin 1B /// regulator of G-protein signalling 5 | UPK1B | 7348 | 4.5 |
| 12 | regulator of G-protein signalling 4 | RGS4 | 5999 | 5.5 |
| 13 | Palmdelphin | PALMD | 54873 | 3.8 |
| 14 | latent transforming growth factor beta binding protein 2 | LTBP2 | 4053 | 3.2 |
| 15 | C-X-C chemokine receptor type 4 | CXCR4 | 7852 | 3.1 |