Table 3.
Cytokines | Vector Mock treated | Vector + 4OHT | K13-ER-Mock treated | K13-ER+4OHT | KSHV Virus | Fold change K13-ER | Fold change KSHV | Fold change based on Microarray data |
IL-1b | 155.5 | 193.5 | 148 | 200 | 200 | 1.3 | 1.3 | 1.07 |
IL-2 | 20 | 23 | 20 | 22 | 21 | 1.1 | 1.05 | 1.01 |
IL-4 | 15 | 15 | 16 | 23 | 17 | 1.4 | 1.06 | -2.9 |
IL-5 | 5 | 5 | 4 | 7 | 5 | 1.75 | 1.25 | 1.2 |
IL-6 | 1946.5 | 2038 | 1043.5 | 10910 | 11242 | 10.45 | 10.77 | 21.17 |
IL-8 | 6115 | 6682 | 4459.5 | 10336 | 10094.5 | 2.31 | 2.26 | 31.5 |
IL-10 | 1023 | 985 | 1003 | 1011.5 | 1038.5 | 1.00 | 1.03 | 3.3 |
IFN-γ | 24.5 | 20 | 21 | 31.5 | 27 | 1.5 | 1.28 | 1.9 |
CSF2 | 13 | 15 | 10 | 1938 | 51 | 193.80 | 5.10 | 15.1 |
TNF-α | 8 | 10 | 9 | 24 | 14 | 2.66 | 1.55 | 5.6 |
EOTAXIN | 5 | 6 | 4 | 10 | 6 | 2.50 | 1.50 | 3.4 |
MCP-1 | 3217 | 2928 | 85 | 13178 | 10235.5 | 155.03 | 120.41 | 71.4 |
MIP-1α | 37.5 | 31 | 24 | 117 | 105 | 4.87 | 4.37 | 3.6 |
MIP-1β | 38 | 43 | 42.5 | 65 | 58 | 1.52 | 1.36 | 1.4 |
CCL5 | 327 | 345.5 | 305.5 | 11126.5 | 197 | 36.42 | 0.644 | 48.3 |
EGF | 8798 | 8695 | 8711 | 8962 | 8765 | 1.02 | 1.00 | 16.5 |
VEGF | 421 | 491 | 466.5 | 479 | 447 | 1.02 | 0.95 | 2.3 |
FGF-β | 415 | 428 | 515 | 615.5 | 500 | 1.19 | 0.97 | 10.7 |
G-CSF | 95 | 104 | 36 | 2125 | 604 | 59.02 | 16.77 | 3.9 |
HGF | 134.5 | 143.5 | 148.5 | 155.5 | 264 | 1.04 | 1.77 | 3.2 |
CXCL10 | 498.5 | 485.5 | 70 | 10453 | 2259 | 149.32 | 32.27 | 47.7 |
IL-12p40 | 21 | 18.5 | 16.5 | 197 | 34 | 11.93 | 2.06 | 97 |
IL-13 | 7 | 8 | 7 | 13 | 8 | 1.85 | 1.14 | 1.4 |
IL-15 | 11 | 12 | 10 | 39 | 12 | 3.90 | 1.20 | 7.8 |
IL-17 | 118 | 139 | 130 | 129 | 132 | 0.99 | 1.01 | -1.3 |
IFN-α | 56 | 60 | 40 | 131 | 98 | 3.27 | 2.45 | 1.4 |
MIG | 13 | 12 | 14 | 39 | 37.5 | 2.78 | 2.67 | 3.8 |
IL-1α | 454.5 | 521.5 | 469 | 752 | 494.5 | 1.60 | 1.05 | 2.3 |
IL-7 | 58 | 50 | 47 | 197 | 181.5 | 4.19 | 3.86 | 2.1 |
IL-1Rα | 30 | 31 | 28.5 | 90 | 59.5 | 3.15 | 2.08 | 3.8 |
IL-2R | 12 | 16 | 15 | 21.5 | 18 | 1.43 | 1.20 | 2.6 |
GROα | 13 | 13 | 14 | 110 | 17 | 7.85 | 1.21 | 7.7 |
MCP-2 | 26.5 | 25 | 23 | 37 | 23 | 1.60 | 1.00 | 4.4 |
MCP-3 | 12 | 14 | 10 | 23 | 372 | 2.30 | 37.20 | 2.3 |