Table 8.
Results From Likelihood Ratio Testing for Goodness of Model Fit in a Comparison of the Restricted Models A–D (See Text) With the General Error Model, Showing the Number of Observed Genotype Pairs and the Number of Discordant Genotype Pairs As Expected Under the Various Error Models
Model | No. of Discordant Genotype Pairs (r02, r01, r12)a | No. of Parameters | Log-Likelihood | λ for Comparison with General Modelb | Degrees of Freedom | P Value |
Observed | 20, 123, 67 | |||||
General model (model A) | 21.5, 122.5, 64.4 | 6 | −46,768.5 | |||
Zero-corner model (model B) | 0.2, 146.3, 87.4 | 4 | −46,834.1 | 131.2 | 2 | <10−3 |
Symmetrical model (model C) | 19.9, 122.1, 68.1 | 3 | −46,772.1 | 7.2 | 3 | 0.07 |
Allele-independent model (model D) | 0.1, 168.7, 61.0 | 1 | −46,861 | 185 | 5 | <10−3 |
No. of parameters in restricted model; r02, r01, and r12 refer to the notation in Table 1.
With λ = −2 × (ln Lrestricted − ln Lgeneral) ∼ χdf2 (6 df).