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. 2008 Dec 13;169(4):497–504. doi: 10.1093/aje/kwn339

Table 1.

Mean Squared Error and Bias of the Estimates of the Interaction Effecta

θge Case-Control Method Case-Only Method Bayes Model Averaging Method
MSE Bias MSE Bias MSE Bias
0 0.023 0.003 0.012 0.004 0.015 0.003
0.1 0.021 0.001 0.020 0.100 0.018 0.037
0.2 0.023 0.002 0.049 0.195 0.027 0.039
0.3 0.020 0.001 0.099 0.297 0.027 0.026
0.4 0.023 0.001 0.169 0.398 0.026 0.009
0.5 0.020 0.003 0.261 0.501 0.020 0.004

Abbreviation: MSE, mean squared error.

a

The odds ratio for the interaction effect was 1.0. The prior weight in the Bayes model averaging approach was set to W = 1:1, with a sample size of 2,000 cases and 2,000 controls in the simulation.