Table 1.

Baseline Characteristics in 1992–1994 of Blue Mountains Eye Study Participants With and Without Incident Early and Late Age-related Macular Degeneration

Baseline Characteristic	None (n = 1,520)a		Incident Early AMD (n = 185)				Incident Late AMD (n = 47)
	Mean (SD)	%	Mean (SD)	%	Relative Risk, Age and Sex Adjustedb	95% Confidence Interval	Mean (SD)	%	Relative Risk, Age and Sex Adjustedb	95% Confidence Interval
Age, years	62.8 (8.05)		68.5 (6.87)*		2.78	2.27, 3.93	72.6 (5.89)*		5.26	3.45, 8.02
Female gender		56.5		61.6	1.21	0.89, 1.66		68.1	1.61	0.86, 3.02
Current smoking		12.6		9.4	1.18	0.70, 2.01		22.2	4.60	2.13, 9.94
Fish consumption ≥1 serving/week		60.7		55.9	0.85	0.60, 1.19		45.0*	0.56	0.29, 1.06
White cell count, × 109/L	6.36 (1.69)		6.36 (1.43)		1.05	0.90, 1.23	6.58 (1.71)		1.21	0.93, 1.57
Plasma fibrinogen, g/L	3.98 (1.27)		4.11 (1.07)		1.00	0.86, 1.17	4.24 (0.97)		1.06	0.81, 1.38
Serum high density lipoprotein, mmol/L	1.43 (0.44)		1.49 (0.42)		1.09	0.92, 1.28	1.37 (0.45)		0.68	0.48, 0.97
CFH rs1061170
TT		41.8		28.7*	1.00			14.9*	1.00
CT		45.6		51.9	1.88	1.23, 2.85		57.6	2.93	1.26, 6.81
CC		12.6		19.5*	2.59	1.52, 4.40		27.7*	5.73	2.23, 14.75

Abbreviations: AMD, age-related macular degeneration; SD, standard deviation.

^*P < 0.05 (significantly different from “none” group, by using the chi-squared test for comparison of proportions and the t test for means).

^aA total of 39 participants with early AMD at baseline were considered at risk of late AMD but not at risk of early AMD. Persons without either late or early AMD at any time point in the study comprised the reference group for this table.

^bRelative risks were estimated per 10-year increase in age, per 1-SD increase in all other continuous variables, and per response (yes vs. no) for all categorical variables, by using discrete logistic models.