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. 2009 Jan 15;169(6):769–779. doi: 10.1093/aje/kwn389

Table 2.

Odds Ratios From Logistic Regression Modelsa for the Probability of Dying Between 2000 and 2006 (n = 933), Social Environment and Biomarkers of Aging Study, Taiwan

Baseline (Model 1)
Standard Risk Factors (Model 2)
Markers of Disease Progression (Model 3)
Nonclinical Markers (Model 4)
All Biomarkers (Model 5)
OR 95% CI OR 95% CI OR 95% CI OR 95% CI OR 95% CI
Sociodemographic factors
    Age 1.117** 1.084, 1.151 1.118** 1.083, 1.155 1.074** 1.036, 1.113 1.105** 1.071, 1.140 1.062** 1.020, 1.106
    Male sex 1.579 0.964, 2.589 1.759* 1.016, 3.046 1.438 0.857, 2.414 1.894* 1.102, 3.254 2.410** 1.277, 4.546
    Any smoking in past 6 months 2.600** 1.617, 4.181 2.401** 1.467, 3.929 2.634** 1.594, 4.351 2.502** 1.523, 4.110 2.612** 1.510, 4.516
Standard risk factors
    Hypertension
    Normal (referent) 1 1
    Prehypertension 0.903 0.471, 1.731 0.948 0.471, 1.911
    Stage 1 hypertension 0.746 0.383, 1.452 0.728 0.354, 1.496
    Stage 2 hypertension 1.404 0.691, 2.854 1.544 0.716, 3.329
    Use of antihypertensive medication 0.834 0.499, 1.395 0.821 0.467, 1.445
    Total cholesterol
    Desirable (referent) 1 1
    Borderline high 0.772 0.486, 1.224 0.866 0.525, 1.429
    High 1.359 0.755, 2.444 1.630 0.843, 3.153
    High density lipoprotein cholesterol
    Low (referent) 1 1
    Normal 0.707 0.449, 1.114 0.755 0.460, 1.240
    High 0.745 0.403, 1.376 0.614 0.314, 1.201
    Body mass indexb
    Underweight 2.808* 1.205, 6.542 1.840 0.728, 4.652
    Normal (referent) 1 1
    Overweight 0.891 0.525, 1.514 1.188 0.655, 2.156
    Obese 0.743 0.381, 1.449 1.332 0.616, 2.879
    High waist circumference 1.262 0.739, 2.154 1.606 0.887, 2.908
    Glycosylated hemoglobin 1.192 0.988, 1.440 1.156 0.939, 1.423
    Use of hypoglycemic agents 0.989 0.466, 2.096 1.156 0.515, 2.595
Markers of disease progression
    Creatinine clearance 0.922** 0.874, 0.971 0.914** 0.864, 0.968
    Creatinine clearance squared 1.000* 1.000, 1.001 1.000* 1.000, 1.001
    Albumin 0.355** 0.177, 0.715 0.428* 0.197, 0.930
    White blood cell count 0.581 0.325, 1.040 0.557 0.297, 1.044
    White blood cell count squared 1.047* 1.006, 1.089 1.042 0.998, 1.087
    Neutrophils 1.027* 1.004, 1.050 1.021 0.996, 1.047
Nonclinical markers
    Epinephrine 0.884 0.741, 1.054 0.906 0.749, 1.094
    Epinephrine squared 1.020** 1.005, 1.035 1.018* 1.002, 1.034
    Norepinephrine 1.004 0.984, 1.025 1.020 0.997, 1.043
    Cortisol 1.005 0.999, 1.011 1.006* 1.000, 1.013
    Dehydroepiandrosterone sulfate 1.000 0.995, 1.004 1.000 0.996, 1.005
    Interleukin-6 1.350** 1.183, 1.541 1.235** 1.064, 1.434
    Interleukin-6 squared 0.991** 0.984, 0.997 0.993 0.987, 1.000
    Insulin-like growth factor 1 0.999 0.995, 1.004 0.999 0.994, 1.004
Log-likelihood −350.7 −339.6 −327.2 −326.2 −299.8
AUC 0.79 0.80 0.82 0.82 0.85
P value from AUC test (vs. model 1) 0.0240 0.0017 0.0027 0.0000

Abbreviations: AUC, area under the receiver operating characteristic curve; CI, confidence interval; OR, odds ratio.

* P < 0.05 (2-sided); **P < 0.01 (2-sided).

a

Models included a random-effect term for the primary sampling units and adjustment for mainlander status, education, urban residence, current chronic conditions, mobility limitations, cognitive function, Center for Epidemiologic Studies Depression Scale (47) score, and self-assessed health status. For definitions of variables, see Table 1.

b

Weight (kg)/height (m)2.