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. 2009 Aug 31;4(8):e6840. doi: 10.1371/journal.pone.0006840

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Tabib et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A. Pre-incubation with HBD does not inhibit the expression of maturation-related molecules DR (upper chart) and CD86 (lower chart) when iDCs are exposed to LPS, whereas pre-incubation with TSP-1 at equimolar concentration inhibits their expression. Data is representative of three experiments. B. Compared to treatment with 10 ng/ml LPS, pre-incubation with different concentrations of HBD (0.4 or 1.0 µg/ml) before exposure to LPS did not have significant influence on expression of either DR (upper chart) or CD86 (lower chart). TSP-1, on the other hand, resulted in a decreased expression of both molecules, similar to that of untreated iDCs. Results are expressed as a percent of the expression of each molecule at the 10 ng/ml LPS treatment, and represent mean±SE of three experiments. Statistically significant difference is marked (*).