Table 4.

ONCOBELL cohort: outcome of EGFR positive (FISH and/or mutation) patients according to MET gene copy number

	EGFR+	MET ≥2.91	MET <2.91	P value
Total	19	11	8
Response rate (N/%)	9/47.4	4/36.3	5/62.5	0.25
Time to progression (months)	3.7	3.9	3.2	0.8
Overall survival (months)	18.7	18.7	5.2	0.25

The table reports response rate, time to progression, and survival of 19 patients included in the ONCOBELL trial EGFR FISH or EGFR mutation positive according to MET mean gene copy number. The median MET mean gene copy number (2.91) was chosen as cut-off value. Also in this particularly selected group of patients, chosen cut-off did not discriminate sensitive versus resistant gefitinib-treated patients.

EGFR, epidermal growth factor receptor.