Table 1.
Characteristics of HNSCC cases and controls
| Controls (n = 548) n (%) | All cases (n = 486) |
Pharynx (n = 204) |
Oral | (n = 189) | Larynx (n = 93) |
||||
| n (%) | OR (95% CI)a | n (%) | OR (95% CI)a | n (%) | OR (95% CI)a | n (%) | OR (95% CI)a | ||
| Gender | |||||||||
| Female | 147 (27%) | 125 (26%) | 41 (20%) | 67 (35%) | 17 (18%) | ||||
| Male | 401 (73%) | 361 (74%) | 163 (80%) | 122 (65%) | 76 (82%) | ||||
| Age (years)b | |||||||||
| Mean (SD) | 61 (11) | 60 (12) | 59 (10) | 59 (14) | 61 (11) | ||||
| Range | 25–89 | 21–91 | 29–86 | 21–87 | 34–91 | ||||
| Race | |||||||||
| White | 500 (91%) | 445 (92%) | 1.0 | 187 (92%) | 1.0 | 174 (92%) | 1.0 | 84 (90%) | 1.0 |
| Non-white | 48 (9%) | 41 (8%) | 0.8 (0.5–1.3) | 17 (8%) | 0.8 (0.4–1.5) | 15 (8%) | 0.8 (0.4–1.4) | 9 (10%) | 0.9 (0.4–2.1) |
| Drinking (drinks/week) | |||||||||
| <5 | 241 (44%) | 133 (27%) | 1.0 | 53 (26%) | 1.0 | 55 (29%) | 1.0 | 25 (27%) | 1.0 |
| >5–15 | 170 (31%) | 109 (22%) | 1.1 (0.8–1.6) | 51 (25%) | 1.3 (0.8–2.0) | 37 (20%) | 1.2 (0.7–1.9) | 21 (23%) | 1.0 (0.5–1.9) |
| >15–30 | 76 (14%) | 95 (20%) | 2.0 (1.4–3.1) | 35 (17%) | 1.7 (1.0–2.9) | 36 (19%) | 2.7 (1.6–4.8) | 24 (26%) | 1.8 (0.9–3.6) |
| >30 | 61 (11%) | 149 (31%) | 3.5 (2.3–5.2) | 65 (32%) | 3.3 (2.0–5.6) | 61 (32%) | 5.6 (3.2–9.9) | 23 (25%) | 1.9 (0.9–3.8) |
| Smoking (pack-years) | |||||||||
| 0 | 182 (33%) | 90 (19%) | 1.0 | 41 (20%) | 1.0 | 44 (23%) | 1.0 | 5 (5%) | 1.0 |
| >0–20 | 154 (28%) | 95 (20%) | 1.2 (0.8–1.7) | 41 (20%) | 1.1 (0.7–1.8) | 39 (21%) | 0.9 (0.6–1.6) | 15 (16%) | 3.5 (1.2–10) |
| >20–45 | 125 (23%) | 131 (27%) | 1.7 (1.2–2.5) | 52 (25%) | 1.5 (0.9–2.5) | 54 (29%) | 1.4 (0.8–2.4) | 25 (27%) | 6.9 (2.5–19) |
| >45 | 87 (16%) | 170 (35%) | 3.2 (2.1–4.7) | 70 (34%) | 2.9 (1.7–4.9) | 52 (28%) | 1.9 (1.1–3.3) | 48 (52%) | 19.7 (7.2–54) |
a
Models include all listed variables; odds ratios not calculated for matching variables (gender and age).
b
For age, summary statistics are presented instead of counts and percentiles.