Table 3.

Patients with CNS relapse (N = 110)^a

Treatment arms	Control (no T)		Experimental (T)
Treatment	A or AC		A–T or AT
	n	%	n	%
CNS relapse	39	100	71	100
Neurological symptoms	29/32	91	58/65	90
Brain metastases	34/38	90	61/67	91
Meningeal carcinomatosis	6/34	18	13/64	20
CNS only disease at death	8/38	21	18/68	26
CNS-R main cause of death	24/38	63	37/68	54
CT scan abnormal due to CNS-R	30/35	86	39/59	66
MRI abnormal due to CNS-R	10/33	30	28/60	47
CSF abnormal due to CNS-R	1/31	3.2	6/59	8.5

^aDenominators indicate numbers of patients with information available.

CNS-R, central nervous system relapse; CSF, cerebrospinal fluid; CT, computed tomography; MRI, magnetic resonance imaging; T, docetaxel; A, doxorubicin; AC, doxorubicin plus cyclophosphamide.